ARAGONA, G. and CUZZOCREA, G.

[Presence of a combined form of vitamin C in the bergamot fruit.].Autier, P., Dore, J. F., Schifflers, E., Cesarini, J.

P., Bollaerts, A., Koelmel, K. F., Gefeller, O., Liabeuf, A., Lejeune, F., Lienard, D., and .Melanoma and use of sunscreens: an Eortc case-control study in Germany, Belgium and France.Berliocchi, L., Ciociaro, A., Russo, R., Cassiano, M. G., Blandini, F., Rotiroti, D., Morrone, L.

A., and Corasaniti, M. T.

Toxic profile of bergamot essential oil on survival and proliferation of SH-SY5Y neuroblastoma cells.Borgatti, M., Mancini, I., Bianchi, N., Guerrini, A., Lampronti, I., Rossi, D., Sacchetti, G., and Gambari, R. Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.Buiarelli, F., Cartoni, G., Coccioli, F., Jasionowska, R., and Mazzarino, M. Analysis of limette and bergamot distilled essential oils by HPLC.Buyukbalci, A. and El, S. N. Determination of in vitro antidiabetic effects, antioxidant activities and phenol contents of some herbal teas.[Effects of aroma hand massage on pain, state anxiety and depression in hospice patients with terminal cancer].Cocks, H.

and Wilson, D. Dangers of the intake of psoralens and subsequent UV exposure producing significant burns.Corasaniti, M. T., Maiuolo, J., Maida, S., Fratto, V., Navarra, M., Russo, R., Amantea, D., Morrone, L.

A., and Bagetta, G. Cell signaling pathways in the mechanisms of neuroprotection afforded by bergamot essential oil against NMDA-induced cell death in vitro.Cottrell, S., Oliver, K., Lake, B. G., and Powell, C. J. Strain-specific enhancement or inhibition of coumarin hepatotoxicity in mice following pretreatment with two different liver enzyme-inducing agents.Crawford, G. H., Katz, K.

A., Ellis, E., and James, W. D. Use of aromatherapy products and increased risk of hand dermatitis in massage therapists.De Pinho, P. G., Falque, E., Castro, M., Oliveira E Silva, Machado, B., and Ferreira, A. C. Further insights into the floral character of Touriga Nacional wines.Dijoux, N., Guingand, Y., Bourgeois, C., Durand, S., Fromageot, C., Combe, C., and Ferret, P.

J.Assessment of the phototoxic hazard of some essential oils using modified 3T3 neutral red uptake assay.Dubertret, L., Serraf-Tircazes, D., Jeanmougin, M., Morliere, P., Averbeck, D., and Young, A. R. Phototoxic properties of perfumes containing bergamot oil on human skin: photoprotective effect of UVA and UVB sunscreens.Fisher, K.

and Phillips, C. In vitro inhibition of vancomycin-susceptible and vancomycin-resistant Enterococcus faecium and E. faecalis in the presence of citrus essential oils.The survival of three strains of Arcobacter butzleri in the presence of lemon, orange and bergamot essential oils and their components in vitro and on food.Gattuso, G., Caristi, C., Gargiulli, C., Bellocco, E., Toscano, G., and Leuzzi, U. Flavonoid glycosides in bergamot juice (Citrus bergamia Risso).Girard, J., Unkovic, J., Delahayes, J., and Lafille, C.

[Phototoxicity of Bergamot oil.The effect of pleasant ambient odour on human visual vigilance.Guerrini, A., Lampronti, I., Bianchi, N., Zuccato, C., Breveglieri, G., Salvatori, F., Mancini, I., Rossi, D., Potenza, R., Chiavilli, F., Sacchetti, G., Gambari, R., and Borgatti, M. Bergamot (Citrus bergamia Risso) fruit extracts as gamma-globin gene expression inducers: phytochemical and functional perspectives.Guth, S., Habermeyer, M., Schrenk, D., and Eisenbrand, G.

Update of the toxicological assessment of furanocoumarins in foodstuffs (Update of the SKLM statement of 23/24 September 2004)--Opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG).Hongratanaworakit, T. Aroma-therapeutic effects of massage blended essential oils on humans.Hotta, M., Nakata, R., Katsukawa, M., Hori, K., Takahashi, S., and Inoue, H. Carvacrol, a component of thyme oil, activates PPARalpha and gamma and suppresses COX-2 expression.[The effects of inhalation of essential oils on the body weight, food efficiency rate and serum leptin of growing SD rats].Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil.Kawaii, S., Tomono, Y., Katase, E., Ogawa, K., and Yano, M. HL-60 differentiating activity and flavonoid content of the readily extractable fraction prepared from citrus juices.Kawaii, S., Tomono, Y., Katase, E., Ogawa, K., and Yano, M. Isolation of furocoumarins from bergamot fruits as HL-60 differentiation-inducing compounds.Kejlova, K., Jirova, D., Bendova, H., Kandarova, H., Weidenhoffer, Z., Kolarova, H., and Liebsch, M.

Phototoxicity of bergamot oil assessed by in vitro techniques in combination with human patch tests.Kimura, M., Mori, T., Suzuki, H., Endo, S., and Kawano, K. EEG Changes in Odor Effects after the Stress of Long Monotonous Work.Kinley, J.

S., Moan, J., Dall'Aqua, F., and Young, A. R. Quantitative assessment of epidermal melanogenesis in C3H/Tif hr/hr mice treated with topical furocoumarins and UVA radiation.Kravkov, S.

W. Light irradiation effect in its dependence upon visual, auditory, and olfactory accessory stimuli.Der Lichtirradiationseffekt im Auge in seiner Abhangigkeit von den Gesichts-, Gehors- und Geruchsnebenreizen.Lake, B. G. and Grasso, P. Comparison of the hepatotoxicity of coumarin in the rat, mouse, and Syrian hamster: a dose and time response study.Luchini, A. C., Rodrigues-Orsi, P., Cestari, S.

H., Seito, L. N., Witaicenis, A., Pellizzon, C. H., and Di Stasi, L.

C. Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis.Makki, S., Treffel, P., Humbert, P., and Agache, P. High-performance liquid chromatographic determination of citropten and bergapten in suction blister fluid after solar product application in humans.Mandalari, G., Bennett, R.

N., Bisignano, G., Saija, A., Dugo, G., Lo Curto, R. B., Faulds, C. B., and Waldron, K.

W. Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction.Mandalari, G., Bennett, R.

N., Kirby, A. R., Lo Curto, R.

B., Bisignano, G., Waldron, K. W., and Faulds, C.

B. Enzymatic hydrolysis of flavonoids and pectic oligosaccharides from bergamot (Citrus bergamia Risso) peel.Mandalari, G., Nueno, Palop C., Tuohy, K., Gibson, G. R., Bennett, R. N., Waldron, K.

W., Bisignano, G., Narbad, A., and Faulds, C. B.In vitro evaluation of the prebiotic activity of a pectic oligosaccharide-rich extract enzymatically derived from bergamot peel.[Accidents due to tanning cosmetics with a base of bergamot oil].Mollace, V., Ragusa, S., Sacco, I., Muscoli, C., Sculco, F., Visalli, V., Palma, E., Muscoli, S., Mondello, L., Dugo, P., Rotiroti, D., and Romeo, F. The protective effect of bergamot oil extract on lecitine-like oxyLDL receptor-1 expression in balloon injury-related neointima formation.Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F.

Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies.Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil.A., and Lake, B.

G. Comparison of the toxicity of allyl alcohol, coumarin and menadione in precision-cut rat, guinea-pig, cynomolgus monkey and human liver slices.Ramful, D., Bahorun, T., Bourdon, E., Tarnus, E., and Aruoma, O.

I. Bioactive phenolics and antioxidant propensity of flavedo extracts of Mauritian citrus fruits: potential prophylactic ingredients for functional foods application.Ratanasavanh, D., Lamiable, D., Biour, M., Guedes, Y., Gersberg, M., Leutenegger, E., and Riche, C.

Metabolism and toxicity of coumarin on cultured human, rat, mouse and rabbit hepatocytes.Romano, L., Battaglia, F., Masucci, L., Sanguinetti, M., Posteraro, B., Plotti, G., Zanetti, S., and Fadda, G. In vitro activity of bergamot natural essence and furocoumarin-free and distilled extracts, and their associations with boric acid, against clinical yeast isolates.Effects of systemic administration of the essential oil of bergamot (BEO) on gross behaviour and EEG power spectra recorded from the rat hippocampus and cerebral cortex.Saitta, M., Di Bella, G., Salvo, F., Lo, Curto S., and Dugo, G. Organochlorine pesticide residues in Italian citrus essential oils, 1991-1996.Sakurada, T., Mizoguchi, H., Kuwahata, H., Katsuyama, S., Komatsu, T., Morrone, L. A., Corasaniti, M. T., Bagetta, G., and Sakurada, S. Intraplantar injection of bergamot essential oil induces peripheral antinociception mediated by opioid mechanism.Sanguinetti, M., Posteraro, B., Romano, L., Battaglia, F., Lopizzo, T., De Carolis, E., and Fadda, G.

In vitro activity of Citrus bergamia (bergamot) oil against clinical isolates of dermatophytes.Schach, H. [EXPERIMENTAL STUDY OF GINGIVAL DRESSING WITH BERGAMOT OIL.].Schach, H. [Simplified method of preparation of the zinc oxide-bergamot oil gingival dressing].Schach, H. [The zinc oxide and bergamot oil gingival dressing and rationale of its preparation].[Effects of the extract from bergamot and boxthorn on the delay of skin aging and hair growth in mice].Stafford, L.

D., Salehi, S., and Waller, B. M. Odors cue memory for odor-associated words.Statti, G. A., Conforti, F., Sacchetti, G., Muzzoli, M., Agrimonti, C., and Menichini, F. Chemical and biological diversity of Bergamot (Citrus bergamia) in relation to environmental factors.Sugawara, Y., Hino, Y., Kawasaki, M., Hara, C., Tamura, K., Sugimoto, N., Yamanishi, Y., Miyauchi, M., Masujima, T., and Aoki, T. Alteration of perceived fragrance of essential oils in relation to type of work: a simple screening test for efficacy of aroma.Treffel, P., Makki, S., Faivre, B., Humbert, P., Blanc, D., and Agache, P.

Citropten and bergapten suction blister fluid concentrations after solar product application in man.Trombetta, D., Cimino, F., Cristani, M., Mandalari, G., Saija, A., Ginestra, G., Speciale, A., Chirafisi, J., Bisignano, G., Waldron, K., Narbad, A., and Faulds, C. B.In vitro protective effects of two extracts from bergamot peels on human endothelial cells exposed to tumor necrosis factor-alpha (TNF-alpha).Uehara, T., Kiyosawa, N., Shimizu, T., Omura, K., Hirode, M., Imazawa, T., Mizukawa, Y., Ono, A., Miyagishima, T., Nagao, T., and Urushidani, T.

Species-specific differences in coumarin-induced hepatotoxicity as an example toxicogenomics-based approach to assessing risk of toxicity to humans.Urbach, F., Forbes, P. D., Davies, R. E., and Berger, D.

Cutaneous photobiology: past, present and future.Wang, L., Sterling, B., and Don, P. Berloque dermatitis induced by "Florida water".Wang, Z., Ling, B., Zhang, R., and Liu, Y.

Docking and molecular dynamics study on the inhibitory activity of coumarins on aldose reductase.Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting.Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S.

R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model.Zacher, K.

D. and Ippen, H. [Contact dermatitis caused by bergamot oil].Zaynoun, S. T., Johnson, B.

E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent.Zaynoun, S. T., Johnson, B.

E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent.Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives.Zhou, S.

F. Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.Naganuma M, Hirose S, Nakayama Y, et al.

A study of the phototoxicity of lemon oil. .

BERGAMOT: Overview, Uses, Side Effects, Precautions, Interactions

[Effects of aroma hand massage on pain, state anxiety and depression in hospice patients with terminal cancer].Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil.The effect of pleasant ambient odour on human visual vigilance.Hongratanaworakit, T. Aroma-therapeutic effects of massage blended essential oils on humans.Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil.Kimura, M., Mori, T., Suzuki, H., Endo, S., and Kawano, K. EEG Changes in Odor Effects after the Stress of Long Monotonous Work.Mandalari, G., Bennett, R. N., Bisignano, G., Saija, A., Dugo, G., Lo Curto, R.

B., Faulds, C. B., and Waldron, K. W.

Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction.Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies.Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil.Statti, G. A., Conforti, F., Sacchetti, G., Muzzoli, M., Agrimonti, C., and Menichini, F. Chemical and biological diversity of Bergamot (Citrus bergamia) in relation to environmental factors.Yasui, Y.

and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting.Young, A. R., Walker, S.

L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L.

Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model.Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent.Zaynoun, S.

T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent.Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives.Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA.Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study.Bruno A, Pandolfo G, Crucitti M, et al. Low-Dose of Bergamot-Derived Polyphenolic Fraction (BPF) Did Not Improve Metabolic Parameters in Second Generation Antipsychotics-Treated Patients: Results from a 60-days Open-Label Study.Cai Y, Xing G, Shen T, Zhang S, Rao J, Shi R.

Effects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo-controlled trial.Cicero AFG, Fogacci F, Bove M, Giovannini M, Borghi C. Three-arm, placebo-controlled, randomized clinical trial evaluating the metabolic effect of a combined nutraceutical containing a bergamot standardized flavonoid extract in dyslipidemic overweight subjects.Da Pozzo E, De Leo M, Faraone I, et al.

Antioxidant and antisenescence effects of bergamot juice.Protective effects of bergamot (Citrus bergamia Risso & Poiteau) juice in rats fed with high-fat diet.Ferlazzo N, Cirmi S, Calapai G, Ventura-Spagnolo E, Gangemi S, Navarra M. Anti-Inflammatory Activity of Citrus bergamia Derivatives: Where Do We Stand?Ferro Y, Montalcini T, Mazza E, et al. Randomized clinical trial: Bergamot citrus and wild cardoon reduce liver steatosis and body weight in non-diabetic individuals aged over 50 years.Florentin M, Liberopoulos E, Elisaf MS, Tsimihodimos V. No effect of fenugreek, bergamot and olive leaf extract on glucose homeostasis in patients with prediabetes: a randomized double-blind placebo-controlled study.The effect of bergamot-derived polyphenolic fraction on LDL small dense particles and non alcoholic fatty liver disease in patients with metabolic syndrome.Gliozzi M, Walker R, Muscoli S, et al.

Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia.Bergamot aromatherapy for medical office-induced anxiety among children with an autism spectrum disorder: A randomized, controlled, blinded clinical trial.Izzo A, D'Arienzo M, Sergiacomi P, Marrese C, Bonucci M, Riccioni C. Prospective Observational Study: The Role of a Bergamot Based Nutraceutical in Dyslipidaemia and Arthralgia for Subjects Undergoing Aromatase Inhibitors Based Therapy.McDonnell B, Newcomb P.

Trial of essential oils to improve sleep for patients in cardiac rehabilitation.The synergistic effect of Citrus bergamia and Cynara cardunculus extracts on vascular inflammation and oxidative stress in non-alcoholic fatty liver disease.Navarra M, Mannucci C, Delbò M, Calapai G. Citrus bergamia essential oil: from basic research to clinical application.Navarro-Triviño FJ, Jadczak P, Ruiz-Villaverde R.

Allergic contact dermatitis caused by Lavandula angustifolia and cross-reaction with Citrus bergamia essential oils in an aromatherapist.Ndao DH, Ladas EJ, Cheng B, Sands SA, Snyder KT, Garvin JH Jr, Kelly KM.Inhalation aromatherapy in children and adolescents undergoing stem cell infusion: results of a placebo-controlled double-blind trial.Pasyar N, Rambod M, Araghi F. The effect of bergamot orange essence on anxiety, salivary cortisol, and alpha amylase in patients prior to laparoscopic cholecystectomy: A controlled trial study.Rombolà L, Scuteri D, Adornetto A, et al.

Anxiolytic-like effects of bergamot essential oil are insensitive to flumazenil in rats.Rondanelli M, Peroni G, Riva A, et al. Bergamot phytosome improved visceral fat and plasma lipid profiles in overweight and obese class I subject with mild hypercholesterolemia: A randomized placebo controlled trial.Toth PP, Patti AM, Nikolic D, et al. Bergamot reduces plasma lipids, atherogenic small dense LDL, and subclinical atherosclerosis in subjects with moderate hypercholesterolemia: A 6 months prospective study.Xiong M, Li Y, Tang P, Zhang Y, Cao M, Ni J, Xing M.

Effectiveness of aromatherapy massage and inhalation on symptoms of depression in Chinese community-dwelling older adults. .

SUCCESSFUL TREATMENT OF VITILIGO

Nadel6 cured a patient by intravenous and oral administration of acridine dyes followed by exposures to ultraviolet rays.Riviere7 suggested that ultraviolet rays enlarge the small blood vessels and facilitate the diapedesis of. .

Novel bergamot oil nanospanlastics combined with PUVB therapy

El-Mofty M, Mostafa WZ, Bosseila M, Youssef R, Esmat S, El Ramly A, et al. A large scale analytical study on efficacy of different photo(chemo)therapeutic modalities in the treatment of psoriasis, vitiligo and mycosis fungoides.Serrano-Pérez JJ, Merchan M, Serrano-Andres L. Photoreactivity of furocoumarins and DNA in PUVA therapy: formation of psoralen– thymine adducts.Systemic PUVA vs. narrowband UVB in the treatment of vitiligo: a randomized controlled study.Bhatnagar A, Kanwar AJ, Parsad D, De D. Comparison of systemic PUVA and NB-UVB in the treatment of vitiligo: an open prospective study.Quantitative assessment of epidermal melanogenesis in C3H/Tif hr/hr mice treated with topical furocoumarins and UVA radiation.Zaynoun S, Johnson B, Frain-Bell W. A study of oil of bergamot and its importance as a phototoxic agent.Hatem S, Nasr M, Moftah NH, Ragai MH, Geneidi AS, Elkheshen SA.Melatonin vitamin C-based nanovesicles for treatment of androgenic alopecia: design, characterization and clinical appraisal.Bseiso EA, Nasr M, Sammour O, Abd El Gawad NA.Comparative enhancement of curcumin cytotoxic photodynamic activity by nanoliposomes and gold nanoparticles with pharmacological appraisal in HepG2 cancer cells and Erlich solid tumor model.Topical colloidal indocyanine green-mediated photodynamic therapy for treatment of basal cell carcinoma.Could nanovesicles containing a penetration enhancer clinically improve the therapeutic outcome in skin fungal diseases?Duodenum-triggered delivery of pravastatin sodium via enteric surface-coated nanovesicular spanlastic dispersions: development, characterization and pharmacokinetic assessments.In vitro stabilization and in vivo improvement of ocular pharmacokinetics of the multitherapeutic agent baicalin: delineating the most suitable vesicular systems.Barakat SS, Nasr M, Ahmed RF, Badawy SS, Mansour S.

Intranasally administered in situ gelling nanocomposite system of dimenhydrinate: preparation, characterization and pharmacodynamic applicability in chemotherapy emesis model.Mouez MA, Nasr M, Abdel-Mottaleb M, Geneidi AS, Mansour S. Composite chitosan-transfersomal vesicles for improved transnasal permeation and bioavailability of verapamil.Bseiso EA, Nasr M, Sammour OA, Abd El Gawad NA.Phospholipid membrane tubulation using ceramide doping “cerosomes”: characterization and clinical application in psoriasis treatment.Lima AM, Pizzol CD, Monteiro FB, Creczynski-Pasa TB, Andrade GP, Ribeiro AO, et al.

Hypericin encapsulated in solid lipid nanoparticles: phototoxicity and photodynamic efficiency.Weiss-Angeli V, Poletto FS, Zancan LR, Baldasso F, Pohlmann AR, Guterres SS.Nanocapsules of octyl methoxycinnamate containing quercetin delayed the photodegradation of both components under ultraviolet A radiation.El Mofty M, Mostafa W, Esmat S, Youssef R, Azzam O, Hunter N, et al.Narrow band ultraviolet B 311 nm in the treatment of vitiligo: two right–left comparison studies.Sezgin-Bayindir Z, Yuksel N. Investigation of formulation variables and excipient interaction on the production of niosomes.Alsarra IA, Bosela AA, Ahmed SM, Mahrous GM.Salama HA, Mahmoud AA, Kamel AO, Abdel Hady M, Awad GA.Soliman SM, Abdelmalak NS, El-Gazayerly ON, Abdelaziz N.

Novel non-ionic surfactant proniosomes for transdermal delivery of lacidipine: optimization using 23 factorial design and in vivo evaluation in rabbits.Effect of edge activators on the formation and transfection efficiency of ultradeformable liposomes.Bayindir ZS, Yuksel N. Characterization of niosomes prepared with various nonionic surfactants for paclitaxel oral delivery.Detoni CB, Cabral-Albuquerque EC, Hohlemweger SV, Sampaio C, Barros TF, Velozo ES.Essential oil from Zanthoxylum tingoassuiba loaded into multilamellar liposomes useful as antimicrobial agents.Sánchez-González L, Chafer M, Chiralt A, Gonzalez-Martinez C. Physical properties of edible chitosan films containing bergamot essential oil and their inhibitory action on Penicillium italicum.de Berker DA, Sakuntabhai A, Diffey BL, Matthews JN, Farr PM.Ortel B, Perl S, Kinaciyan T, Calzavara-Pinton PG, Honigsmann H.

Comparison of narrow-band (311 nm) UVB and broad-band UVA after oral or bath-water 8-methoxypsoralen in the treatment of psoriasis. .

Bergamot Oil Uses and Benefits

If you’re a fan of Earl Grey tea, you’re already enjoying the distinctive taste of bergamot, which is used to flavor it.It’s currently grown in many parts of the world, but achieved its prominence and name in the town of Bergamo in southern Italy.Add two to five drops of Bergamot essential oil to products such as body wash, shampoo, and facial scrubs.This may make bergamot oil an effective spot treatment for acne in people who do not have sensitive skin.Touted for its antibacterial properties, tea tree oil may fight acne and soothe skin inflammation.Touted for its antibacterial properties, tea tree oil may fight acne and soothe skin inflammation.These include: Stress reduction A small 2015 study done on women in Japan found that inhaled bergamot oil mixed with water vapor reduced feelings of anxiety and fatigue.Similarly, a 2013 article published in the journal Current Drug Targets reported that aromatherapy with bergamot (among other essential oils) can relieve depression, anxiety, and other mood disorders by signaling the brain to release dopamine and serotonin.Fights food poisoning Linalool, a compound found in bergamot, may sometimes be effective at destroying types of bacteria responsible for food-borne illnesses.A 2006 study examined bergamot’s effectiveness at destroying several strains of bacterium on chicken skin and cabbage leaves.A 2016 study tested the effect of different types of bergamot essential oil against strains of Listeria monocytogenes, the bacteria that causes listeriosis infection.The different formulations of bergamot had weak to strong effects at stopping the growth of the different bacteria samples.Given the variability, researchers concluded that bergamot essential oil’s effectiveness against bacteria in foods should be estimated.Lowers cholesterol A 2016 review of human and animal studies indicated that flavonoids found in bergamot can help reduce lipid levels, although it indicated that the exact mechanism driving this result is unclear.A 2017 review of studies analyzed the effects of multiple essential oil compounds on the pain response and other conditions in humans and animals.It found that both linalool and carvacrol had analgesic, anticonvulsant, and anti-inflammatory capabilities when used in a variety of methods that included applying it on the skin.Be aware that using essential oils in a diffuser can have a negative effect on children, pets, or pregnant women. .

21 Natural Ways To Get Rid Of White Spots On Skin (Vitiligo)p

Massage the coconut oil on the affected areas during the day and night as well.Coconut oil is often used in vitiligo treatment lotions and creams.Cut open the leaf and extract the gel present inside.Aloe vera has healing properties and nutrients that will help remove the white spots and keep your skin hydrated (6).A study published in the European Journal of Dermatology showed that khellin components were helpful in treating vitiligo (7).Mix the oils and massage the affected area with this blend.This essential oil is often recommended in Ayurvedic and Unani medicine to treat various skin conditions like psoriasis, eczema, and vitiligo.Apply a mixture of the oils on the white spots on your skin.Black pepper oil contains a compound called piperine.This compound activates the inactive melanocytes (cells that produce melanin), thus restoring the skin color (9).Just add the essential oil to a small dollop of the cream and mix well.Bergamottin, a compound found in bergamot essential oil, acts as a natural photosensitizer (10).Mix the oils and apply the mixture on the affected area using the cotton ball.This versatile essential oil has the ability to darken white vitiligo spots because of its immune-stimulating and anti-inflammatory properties (11).Gingko biloba herb is an amazing home remedy for vitiligo.It will not only slow down the progression of the disease, but also help in repigmenting the white patches on your skin if you continuously use it.Apply this as directed on the bottle on the white patches on your skin.A common deficiency in vitiligo patients is that of vitamin B12.This vitamin plays a key role in the development of red blood cells.Its deficiency can cause anemia and white spots or vitiligo.If you suspect that you are suffering from a vitamin B12 deficiency, get yourself tested immediately.Supplementation with vitamin B12 and folic acid has been shown to work for vitiligo patients to restore pigmentation and also control the spread of the disease (14, 15).Apply the ginger juice on the affected area and leave it on for about 20 minutes.It is also an anti-inflammatory agent and contains plenty of antioxidants that restore the skin’s health (16).Eating celery can help cure white spots on your face.Psoralens help the skin react to sunlight in a proper way, thus reducing the chances of white spots appearing in the first place (18).The other ingredients in this green juice have skin regenerative properties.Drink a glass of fresh carrot juice daily.It helps in repigmentation of the skin and also protects it from sun damage.Carrots also contain psoralens that are recommended for vitiligo treatment (19).Just like carrot, beetroot is also rich in pigments that can help to restore the skin’s hypopigmentation.Brew some fresh green tea and let it cool down to room temperature.The extracts from green tea will help to remove white spots on the face to a great extent.This is because green tea contains plenty of antioxidants that will heal the skin by removing the free radicals that are damaging it (20).You can either rub the papaya pieces directly on the white spots or mash them and apply as a layer.It helps to revive melanin, the skin’s natural pigment, and restore the color in the hypopigmented areas (21).Apply this on the white spots and leave it on for a couple of hours.The topical application of turmeric and mustard oil works wonders for vitiligo.Mix the ingredients and gently rub the affected areas with the paste.Ginger juice is a good stimulant for blood circulation, and it also contains antioxidants.This copper is also effective in bringing back the skin’s color in the white patches formed because of vitiligo (24).Crush the radish seeds into a fine powder and mix it with the vinegar to make a smooth paste.Do this daily for six months, and you will see the white patches disappearing gradually.Radish seeds are very effective in regenerating melanin in human skin due to their healing properties.Honey is beneficial in killing bacteria and fungus because of its antifungal and antibacterial components.Along with sandalwood, the anti-inflammatory and antioxidant components of both the ingredients will fade away your white spots easily (28).Add a few drops to any carrier oil and massage the affected area with it for a few minutes.Neem is a very good natural remedy for treating all kinds of skin problems.Neem leaves can help you regain the original color of the skin (29).Apply this topically on the white spots on your face and body.Leave it on for 5-10 minutes so that the skin can react with the cabbage juice, which can cure the white spots.Cabbage juice is the one-stop solution for skin ailments like vitiligo.Its healing properties can be attributed to the amino acid methionine found in it (30).Store water overnight in the copper vessel at room temperature.The immune boosting property of copper is good for the treatment of vitiligo.This will help to produce melanin in the body when it is consumed on a daily basis, thus leading to restoring the pigmentation in the white spots.Boil the roots of Mama Cadela plant in water for about 10-15 minutes.Mama Cadela roots are also effective in reducing the white spots.The active ingredients bergapten and psoralen are effective in treating depigmented skin (32).Just soak tamarind and Psoralen seeds in water for four days.Dry the seed mixture and grind it to a coarse paste using the same water used for soaking.You can also mix equal quantities of Psoralen seed powder with Barberry root powder, black cumin, and some coconut oil.Mix them to form a smooth paste and apply the mixture on the white patches on your skin.Repeat the process once or twice daily to reduce white patches on the skin.Psoralen herb is an effective home remedy for vitiligo.The seeds of the herb are used to treat white patches on the skin.It interrupts the pathways that cause a hindrance in the production of melanin (33, 34).Gently crush the leaves and add the lemon juice to it.Holy basil, when directly applied to the affected areas, can help you get rid of patches.These natural remedies will not act like magic to reduce white spots.Yes, you can surely go for medicines and other treatments to reduce white spots, but they may have unwanted side effects.It is best to stick to natural home remedies and a proper diet to reduce these white spots.This will protect you from the harmful UVA and UVB rays of the sun.It will help to reduce the vitiligo signs on the skin and tanning as well.If you have a fair complexion and vitiligo as well, then it is important that you apply sunscreen with SPF 30.This will protect you from the harmful UVA and UVB rays of the sun.It will help to reduce the vitiligo signs on the skin and tanning as well.A small cut or abrasion will not only cause bleeding and pain, but there are also high chances of vitiligo developing in the bruised areas.A small cut or abrasion will not only cause bleeding and pain, but there are also high chances of vitiligo developing in the bruised areas.Wash your face regularly with a soap that hydrates your skin.Avoid using soaps that contain chemicals that will have a harsh effect on the skin.Make sure you exfoliate your skin and remove the dead cells regularly.Clean your skin twice a day with a mild astringent to keep bacteria and fungi at bay.Visit your doctor to find out whether fungal infections are responsible for the white spots on the skin or if it is vitiligo.Sometimes, vitiligo can happen due to lack of a nutritious diet.You should have a wholesome and balanced diet to prevent vitiligo problems affecting your skin.Expert Ayurvedic practitioners prescribe a special diet to cure vitiligo.This diet should be followed continuously for 40 days along with the external application of natural medicines.They recommend you follow a vegetarian diet and have 600 grams of raw cucumber thrice a day.You also need to have three betel leaves thrice a day, along with raw cucumber, to reduce vitiligo.If you are interested in this kind of diet, consult a certified Ayurvedic doctor for a detailed version of it.Consumption of dairy products like milk and yogurt should be kept to a minimum.Friction and pressure are factors that have been responsible for them to spread and form new patches.Some examples include rubbing due to jewelry or clothing, skin injury, and physical trauma.Vitiligo can happen at any age, but it generally starts before the person turns 20.Premature whitening or graying of the hair on your scalp, eyelashes, eyebrows or beard before you turn 35 years of age.Discolored patches in the armpits, navel, genitals, and rectum.Change in the color of the mucous membranes that line the insides of your mouth and nose.Prep the skin first by washing it with an antibacterial and patting it dry.Taking a picture of the affected area in a set lighting will help you monitor if the patches have repigmented.The fading away of the discoloration and the skin regaining its color are the recovery signs for vitiligo.It might be hereditary as about 30% of the patients with it have a family member who is suffering from vitiligo.However, there is no guarantee or solid proof so far to prove that vitiligo is hereditary.Vitiligo can appear on any part of the body, be it the back, chest, face, neck, hands, and feet or even the genitals.Also, having other autoimmune disorders such as Hashimoto’s thyroiditis increase the risk of developing vitiligo (37).Get the diagnosis of vitiligo done as early as possible and take charge of the situation.Since your skin mirrors your health, you have to analyze the root cause of the white spots.If it is your health that is causing the white spots, then seek immediate medical assistance. .

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